Pregabalin IP 300mg Capsules – Detailed Overview
Indications
- Neuropathic Pain:
Pregabalin is effective in managing nerve-related pain caused by conditions such as diabetic neuropathy, postherpetic neuralgia (shingles), spinal cord injury, and other neuropathic disorders.
- Epilepsy:
Used as an adjunctive treatment for adults with partial-onset seizures, helping to reduce seizure frequency.
- Fibromyalgia:
Helps relieve widespread muscle pain, tenderness, and discomfort associated with fibromyalgia.
- Generalized Anxiety Disorder (GAD):
Approved in some regions for the treatment of GAD, helping to reduce anxiety symptoms.
Dosage
- Neuropathic Pain: Usually starts at 150 mg per day, divided into two or three doses. Based on response, the dose may be increased to 300 mg per day after one week. The maximum recommended dose is 600 mg per day.
- Epilepsy: Typically begins at 150 mg per day and may be increased gradually up to 600 mg per day depending on response.
- Fibromyalgia: Often starts at 75 mg twice daily (150 mg/day) and can be increased to 300 mg per day. Some patients may require up to 450 mg per day.
- GAD: Dosage varies but usually follows a gradual dose-increase approach based on effectiveness and tolerance.
Side Effects
Common side effects may include:
- Dizziness
- Drowsiness
- Dry mouth
- Swelling of hands or feet
- Blurred vision
- Weight gain
- Difficulty concentrating
Less common but serious side effects include allergic reactions, mood changes, suicidal thoughts, angioedema, and severe muscle pain or weakness.
Precautions
- Kidney Function: Dose adjustment is required in patients with kidney impairment.
- Pregnancy & Breastfeeding: Should be used only if clearly needed and prescribed by a healthcare provider.
- Alcohol & CNS Depressants: Alcohol and sedatives may increase dizziness and drowsiness.
- Withdrawal: Pregabalin should not be stopped suddenly; doses should be reduced gradually under medical supervision.
Storage
Store at room temperature, away from moisture and light. Keep out of reach of children.
Administration Tips
Capsules should be swallowed whole with water and can be taken with or without food. Taking doses at the same time each day helps maintain consistent medication levels.
Always consult a healthcare professional before starting or adjusting Pregabalin IP 300mg to ensure safe and effective use.